GENERAL
Rectal ozone insufflations are a powerful adjunct to the treatment of infectious and inflammatory conditions of the digestive tract. Ozone provides dramatic improvement in Proctitis, Proctocolitis, Enterocolitis, and Enteritis frequently encountered in homosexual men, patients with clinical AIDS, and women engaging in frequent promiscuous rectal intercourse. Rectal ozone promptly sterilizes the surface of the rectum and colon, and considerably reduces the amount of infectious agents, especially anaerobic bacteria, in the colon and, to a lesser extent in the small intestine.

CONDITIONS TREATABLE WITH RECTAL OZONE INSUFFLATIONS

Infectious Agents
The most common infectious agents reduced or eliminated by rectal ozone are Entamoeba histolytica, Giardia lamblia, Campylobacterjejuni, Clostridium difficile, Shigella spp., Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum, HSV, Mycoplasma hominis, Ureaplasma urealyticum, group B streptococci, HAV, HBV, etc., and in patients with clinical AIDS also CMV, Cryptosporidium spp, lsospora spp, Mycobacterium avium-intracellular (MAI), HIV, etc. Rectal ozone is effective for the treatment of sexually acquired proctitis most commonly from N. gonorrhoea, HSV, and C. trachomatis, less commonly U. urealyticum, C. albicans, T vaginalis, T pallidum, H. ducreyi, Calymmatobacterium (formerly Donovania) granulomatis, HBV, HIV, CMV, EBV, and human papillomavirus; as well as sexually acquired proctocolitis, enterocolitis, and enteritis due to Campylobacter spp, Shigella spp, E. histolytica, G. lamblia, and others.

Diarrheas
Rectal ozone is a valuable adjunct in treating massive dehydrating diarrheas from Vibrio cholerae, toxigenic Escherichia coli (ETC strains), Giardia lamblia, Rotavirus and Norwalk agents; of bloody, mucopurulent diarrheas caused by Shigella spp, invasive E. coli (EIEC and EHEC strains), Entamoeba histolytica, Clostridium difficile, Campylobacterjejuni, and Salmonella spp; and of mixed or variable acute diarrheas from Yersinia enterocolitica and Cryptosporidium.

Food Poisoning
Ozone may be helpful for the treatment of Food Poisoning from Clostridium perfringens, Bacillus cereus, and Staphylococcus aureus, and for Traveler's Diarrhea from toxigenic and invasive E. coli (ETEC and EPEC strains, respectively), Shigella and Salmonella spp, Giardia lamblia, and others. A detailed discussion of food poisoning can be found under IV, and of fish and shellfish poisoning under V of this chapter.

Inflammatory Bowel Disease
Rectal ozone is an important adjunct in the treatment of Inflammatory Bowel Disease such as Ulcerative Colitis and Crohn Disease, Pancolitis, Amebiasis, Procto-sigmoiditis, Radiation Enteritis and Colitis, Intestinal Tuberculosis, Diverticulitis, Toxic Megacolon, Perianal Fistulas, Fissures, and Abscesses, Irritable Bowel Syndrome, as well as hemorrhoids.

LIVER DISEASE
Rectal and systemic ozone are among the most effective adjunct treatments for Liver Disease of all types including:

Alcoholic Liver Disease
Acute and Chronic Viral and Immune Hepatitis
Primary Hepatocellular Cancer and other hepatobiliary neoplasms
Cholestatic Syndromes
Cirrhosis of the Liver
Rectal ozone is absorbed in small amounts through the rectal and colonic mucosa into the portal circulation and significantly improves the liverfunction. Ozone also removes toxins, eliminates infectious agents and harmful immune complexes that may contribute to liver disease, and helps destroy malignant growths. Ozone is also indicated as adjunct treatment for esophageal varices and hemorrhoids caused by liver dysfunction.

The LSU treatment program for acute liver failure is discussed in Appendix B, under IV, d. Treatment of Mushroom Poisoning (and Acute Liver Failure).

REITER SYNDROME
Rectal and systemic ozone are effective in Reiter syndrome or rather Reactive Arthritis triggered by enteric infections with Shigella spp, especially Sh. flexneri, rarely Sh. sonnei, Sh. boydii, and Sh. dysenteriae, Salmonella spp, Yersinia, and Campylobacter species, especially C jejuni, or with Clostridium difficile, Brucella spp [see F, III, B, 7, and especially footnote of G, III, b, 4], and genital infections with Chlamydia trachomatis (in women, use additional vaginal ozone applications, see G), and possibly other agents.

COLONIC IRRIGATIONS
Colonic irrigations for cleansing, both for generally healthy people and patients with degenerative disease, are greatly enhanced by adding ozone to the irrigation fluid. LSU has for decades recommended ozonated colonic irrigations to improve the effectiveness of this most valuable cleansing method.